We generate novel and useful enzymes and organisms for applications in medicine, neurobiology, chemical synthesis and alternative energy. We also construct entire synthetic families of enzymes and other proteins in order to study structure-function relationships free from constraints of natural selection.
This research requires contributions from many disciplines, including chemistry, bioengineering, biochemistry, molecular biology, microbiology, chemical engineering, chemistry and applied physics.
Farwell et al., ACS Central Science 1, 89-93 (2015). doi: 10.1021/acscentsci.5b00056